Denis studied Technical Biology at the University of Stuttgart and Harvard University. He did his research thesis in the laboratory of Prof. Alfred Goldberg at the Harvard Medical School working on protein degradation and proteome dynamics. Moving from wet lab to dry lab, he joined the Complex Systems Modeling group as an intern at Bayer AG where he was working on mechanistic computer models describing the physiology-based distribution of substances in the body (PBPK modeling). Such a classical engineering approach in biology fascinated him so much that he continued working in the field of Systems Biology by joining the laboratory of Prof. Peter Sorger at the Harvard Medical School for his diploma thesis where he focused on Rheumatoid Arthritis. Afterwards he joined the Systems Biology PhD program and he is currently working in the laboratory of Prof. Bernd Bodenmiller in the area of single cell proteomics using Imaging Mass Cytometry. Besides his contributions to the Life Science Zurich Young Scientist Network, he is the Vice President of the Student Council of Switzerland of the International Society of Computational Biology.